Thanks Daniel, for testing I changed the FQDN directly to one of my StoreFronts and there are no issues ATM. Wondering, I set the correct sourceip persistence at my SF LB like described here
https://www.carlstalhood.com/storefront-load-balancing-citrix-adc/#vserver and timeout 480 is the same as the timeout on my StoreFront Web settings. Is there another setting or option causing different session persistences?