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Are you just looking for a working base for Defender settings/exclusions? My environment isn't like for like with what you describe, but may be close enough (W10 20H2 single session, FSL, WEM, Teams). If it is, here's a report of my Defender GPO settings (minus the onboarding stuff).

@Nick Panaccio you are a gentleman, owe you a beer… @Matt Nation @Shane Kleinert let's compare against what we have tomorrow

Nice @Nick Panaccio. You rock bro.

metallica