Anyone using Zerto Draas with MCS to replicate their images/clones to another site? It appears it logically remap datastores and I know MCS doesn't like datastore changes

What is the hypervisor? Newer versions of Image Management support replicating prepared images to different sites after preparation.

VMware

Here you go. https://docs.citrix.com/en-us/citrix-virtual-apps-desktops/install-configure/image-management#introduction You can master an image on 1 vcenter storage, and then replicate it to another vcenter for catalog creation.