We are seeing an issue on Workspaces Pools with *certificate-based Authentication (*CBA) enabled that published Citrix XenApp apps to the Start Menu of the Workspaces Pools desktop launch but get a message "The user name or password is incorrect. Try again". If I turn off CBA, and log in to the desktop with AD credentials it works ok. I found an Citrix article
https://support.citrix.com/s/article/CTX289690-unable-to-start-session-in-double-hop-environment?language=en_US that has a similar issue that mentions FAS, we don't have FAS deployed in our Citrix envionment. Is it required to get it to work? Wasn't sure whether anyone else has encountered this?