So W10/W10 single session or Serer 2019/2022 can be nonpersistent golden images. You can choose to use MCS Random(pooled) or PVS.
The golden image has what you install, and then that is pushed out. If using Random/Pooled/Non-persistent, then yes, whatever the user does, meaning settings are typically grabbed by the profile management solution. Then, the VDA/PVS Targets reboot, and the image is nulled out and reverts back to the golden image on reboot = Non-persistent, for example.
The golden image is persistent, but the VDAs or PVS targets are non-persistent, for example.
However, you can also do Dedicated MCS Clones. So you can have an MCS golden image that will push out VDAs, but the machines can be Full clones. Therefore, the VDAs are treated as persistent machines, for example.
It's all about what provisioning method you choose.
Hopefully I answered you