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Have had it enabled for years. It is suppose to provide better perfomance so I have it on: https://learn.microsoft.com/en-us/azure/storage/files/storage-files-smb-multichannel-performance

FSLogix doesn't do any thing special to support this. FSLogix uses the built-in SMB client in Windows and if the client OS supports multi-channel, FSLogix will take advantage of it. FSLogix Docs - SMB File Shares