Should be one location. Either profile or Office one. I went and looked at my notes, and I have one setup where I put it in the Profile side, then I have another setup where I put it in the Office Containers. I don't recall why I did it. Unless anyone else has a better why to put it in profile container vs Outlook Container for this specific setting?
The profile container will write here "HKEY_LOCAL_MACHINE\SOFTWARE\FSLogix\Profile"
or if used in outlook container it will write here
HKEY_LOCAL_MACHINE\SOFTWARE\SOFTWARE\Policies\FSLogix\ODFC