Hello, I was wondering how does the pipeline handles mature miRNAs that have identical sequences but come from different hairpins (for example, hsa-miR-512-5p and hsa-miR-498-5p) in mirtop output (the mirna.tsv table) ?
I understand that the idential miRNAs will have same UIDs and we will only keep one of them, but what about the variants?
I mean, lets suppose that the mature miRNA A is identical to miRNA B, so counts of the exact mature (e.i. NA variant) is assigned to for example miRNA A. But then we have a counts of a variant that is unique to miRNA B, the counts assigned to miRNA B will only come from this variant?
Just trying to understand how to interpret the counts here. Thanks!