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Sounds like it's single threaded JavaScript - unless an app is designed to leverage GPU you won't see much benefit other than perhaps recovering a bit of CPU from the protocol compression that can be used by the app. https://medium.com/salesforce-architects/optimizing-lightning-performance-on-citrix-virtual-apps-and-desktops-850c8c965736 and https://www.linkedin.com/pulse/salesforce-lightning-citrix-chris-barker/ - both suggest as single-threaded more cores won't help and although a bit old - there's no real suggestion any one has done anything to offload the compute - i haven't got any direct experience with lightning myself but my experience with other apps I doubt GPUs are the answer

Yeah i seen both of those articles and it doesn't really offer many solutions apart from yeah its slower on multi user systems and suggests to scale out and buy faster hardware. The spec's of our hosts is pretty good they are Dell R740's with x2 Xeon Gold 6248 cpu's @ 2.5Ghz with 20 cores per socket so 80 logical cores with hyperthreading. Bios power management settings are set to high performance as well. We have practically zero over commitment x5 Vm's on the hypervisor host with 10 VCPU/100GB memory

No experience on Citrix but on a very fast laptop at my previous employer and it was frikkin’ slow there. Everyone there switched back to classic due to this

Yeah it seems classic Salesforce is way faster

Nice specs but if a vendor is determined to write a single-threaded CPU hungry app... years and I mean years and years ago a lot of the CAD apps were heavily single-threaded and CPU hungry and then weren't optimised to take advantage of GPUs and there was a lot of fiddling with apps like Catia using Turbo mode - https://virtuallyvisual.wordpress.com/2016/04/27/monitoring-nvidia-vgpu-for-citrix-xenserver-including-with-xencenter/ has a section on it... can't really remember any details but .... probably one to raise a ticket with Salesforce over as sounds like the app itself isn't really designed for virtualisation.