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e.g. http://bbc.co.uk redirects to http://bbc.com for US-users but stays at http://bbc.co.uk when browsing from the UK.

Is there GSLB type DNS responses going on here?

Only with a proxy that I know of Carl. We have the same issue in the UK with some US sites.

UK Proxy or BCR and break out the traffic locally on your UK endpoints for those websites

Good shout @dready. Or put VDAs in the UK, I guess that's not an option though.

A danish customer of mine, with US based users, have set up a proxy in the US to be able to provide US content, before the proxy they all had danish based content.