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Do you use ADC or VPN? EDT doesn't detect MTU size. So you need to lower that manually in some scenarios.

No, direct (LAN) in this case.

Do you use default MTU (1500/1512) on your network? Are you seeing packet fragmentation on the endpoint (using Wireshark)?

Sorry for tardy reply. Yes, default MTUs, haven’t looked at fragmentation, will check it out. Is there a recommendation from Citrix on MTU?

No as it depends on your situation. But with ADC I would recommend 1480