You don't need AV if Crowdstrile is installed. It's like having two AV working at the same time. Which has a huge impact on the performances as both are acting like the other one is a virus (no matter what the vendors say "they are compatible").
Just put Windows Defender in passive mode (installed but inactive, can be called for a regular analysis if you need).
A part from that, even in CrowdStrike, put in place the exception list. VDI=1 switch is here to say "MultiSession and Ephemeral environment"