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You should use OnDemand sync to keep from everything downloading into the profile. Then you can use something like storage sense or a script like mentioned in this: https://learn.microsoft.com/en-us/answers/questions/643601/fslogix-onedrive-for-business-cache-non-persistent

Files on Demand and storage sense with profile shrinking But try this for a temp solution (test this first) <Exclude Copy=“0″>AppData\Local\OneDrive\cache</Exclude>

Thank you @Ray Davis . Yea it is in place