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Technically there is alot that comes into play when files are deleting in one place but not the other. The first being there a syncing in progress in either the local device or the VDI. When you have multiple devices syncing files with OneDrive, conflicts can occur if changes are made simultaneously on different devices. OneDrive may resolve these conflicts by deleting files it considers duplicates. Check if any conflicts have been reported in the OneDrive interface or event logs. These are the sync folders on my test environment the VDI user is able to sync down from OneDrive. [2:58 PM] Files On-Demand are a headache in VDI if there are no DehydrateSyncedTeamSitespolices in place. For example if you click on a shared sharepoint site the files-on demand will start downloading that entire site to your local machine or vdi and you will run out of space very quickly. check to see if the files that are being deleted are in any of those sync folders.

Thank you Holmand. In my case, One Drive automatically starts deleting the files which user has saved in One Drive ( in local machine)

what kind of profilesolution are you using? fslogix or upm? We've seen the same issue if there was a problem mounting the profilecontainer in fslogix

@Tom Berntsen, Thank you for your message. We are using UPM

Sorry been out of town for a while. We didn't really do much, it was due to a issue with one of the profile servers. Which UPM version are you running?

@Tom Berntsen, No problem Tom.. We are using Citrix Profile Manager