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Is this for use with Storefront of workspace service?

workspace service, my friend

Ideally a pair of FAS servers in each resource location for redundancy. But they can be the same pair of servers linked to each RL if you have internal inteconnetivity between physical locations.

Agree with Paul you can also in workspace define the other datacenter as a secondary. The good thing about Workspace Service versus Storefront is that if FAS doesn't work with Workspace the user will get prompted for creds. That does not happen with Storefront in many fault scenarios. Remember to include all of the FAS servers in the GPO applied to the FAS servers and VDAs is you are using the backups too.