23andMe alternative in India?

for dna testing and all, there are dnalabs

https://www.xcode.in/ I got my DNA analysed from these guys. You need to buy one of their reports (similar to 23andme) -- but you can write to them and request your code dump (which comes as a text file).

Saurabh, Did you undertake it for all reports and do you recommend xcode.in? I am intrigued and didn't know about it before

@mysterious-yak-23452 I got this one: https://www.xcode.in/gene-health/ They send you a detailed 60-70 page report highlighting what are the most probably causes of your death, etc.

Thank you. Learnt something new!

Most people in US do genetic testing to know their lineage (%dutch, %native american etc) and identify lost relatives/cousins. Those motivations don’t apply to India and data too doesn’t exist that well. If your motivation is around wellness (diet, exercise etc); then the research is weak and most inferences they show can be self-fulfilling or inactionable for average joe. Might be relevant for athletes etc. If your motivation is around rare diseases (single gene mutation leads to a disease/syndrome), you will get high confidence results but its a rare and unless you have family history / indicative symptoms not useful for adults. For lifestyle diseases like Diabetes, Heart Conditions etc; there is a bit of research but its very indicative. Instead of genetic testing, you might as well look at both sides of your family for risk and your own lifestyle to judge the risk. A colleague and I have done DNA tests for ourselves as part of product category evaluation back in 2019. We felt indifferent and didn’t change one thing in our lives post that. A well known founder does DNA testing every year to see progress the field is making and he too is of opinion that actionable insights for an average person is weak and not worth the cost you pay. So who needs to get genetic testing done? • Prenatal fetus • New borns • Folks with family history of rare diseases • Folks with indicative symptoms of rare diseases • Targeting genetic testing for a particular disease or treatment protocol (which drug might work for you with strong research) • Ethnicity Data (for well studied population) • You have money to spare to satiate your curiosity • You want raw DNA data (Saurabh’s motivation I guess) for future use / optionality. You can check this data against latest research Genetic testing is expensive unless your order is given in bulk to a lab. Very less wellness research is done on Indian population due to cost factors. Your data might be sold by these companies for research purposes. Your data can be requested by govt authorities in future (in US this happens already). Sorry for the long post. Spent sometime on this space 3 years back. Read The Gene by Siddharth Mukherjee to understand the promise and uncertainty in this field.

A well known founder does DNA testing every year

@loud-artist-61521 Can you explain this bit. Why does he test every year?

Few reasons: 1. There are always new startups popping up and he wants to evaluate them 2. Very few companies do full DNA sequence (it is lot more expensive 1L vs say 10k). They mostly do a panel and these panels get changed by the company. 3. Each company can have different algorithms to interpret research data (some have exclusive/early access to some data) so inferences change. 4. He is a consumer guy and wants to judge how they communicate and educate end users of their reports. So he gets to do that. 5. He is a health freak and wants to see if anyone is pushing the envelope here. Mostly its someone with money throwing money at a very open-ended problem