@creamy-bird-1828 I am going to hazard a guess and say No. To get tax deductions in India for donations, the receiving entity needs to be registered in India under the Section 80G clause of the Income Tax Act. If your 501c (3) company isn’t registered in India under 80G (which I assume in your case), then this mostly won’t be applicable.
https://cleartax.in/s/donation-under-section-80g-and-80gga