I guess the site has crashed? page isn't even load...
# random
k
I guess the site has crashed? page isn't even loading properly
😞 2
m
it was expected tbh
m
I clicked on Register, and it freezed
k
message has been deleted
😂 9
m
Fml
f
When a tatkal ticket for a train is like a gamble, because only people supposed to travel in a specific train are trying to book. I’m not surprised this happened, just the sheer scale of problem is insane.
f
So much mismanagement. Unbelievable. In UP they are filing FIRs against people/doctors asking for help with oxygen cylinders
k
It was expected by everyone, which I why I thought the expert govt will atleast take care of these huge server load issues.
m
I was able to Register, but vaccination slots are not available?
f
We’re competing with potentially this many people on a govt. built platform. party parrot
🤯 2
m
What scares me more, is the process after 1st May. How with such large population? When government struggled with 45+
q
Abhi start bhi nhi hua, aur already extend hogya ☹️
🤦🏻‍♂️ 1
🤦‍♂️ 1
f
Between the two vaccine variants which one is more effective (as per data) ?
➕ 1
f
So far it is only Covaxin that I’d trust, saw multiple instances of people around me not getting infected or only mild infection with just first dose alone.
➕ 1
m
A lot of medical students (my brother as well ) are getting Covaxin
f
The entire misinformation/defamation campaign when Covaxin got emergency approval in India back in January is mind-boggling tbh (which may also have contributed to the scary 2nd wave we’re in). Bharat Biotech is an industry veteran and they weren’t fucking around when they made this vaccine, their Rotavirus and Hepatitis vaccines are in the market for ages now.
q
COVAXIN. I am sure you guys, must have seen this today!!
m
Tbh, I don’t mind going to the private hospital and pay a hefty amount at this point.
☝️ 4
As I saw my parents doing multiple trips to the Vacc Centers, and then discovering it is out of Stock.
k
Same here, I'm okay with paying a premium for the vaccine.
q
But the problem I think is manufacturing COVAXIN in huge volume. SII is manufacturing covidshield, and being the largest vaccine manufacturer, it is available in "abundance". In Mumbai, I saw it on news few weeks ago, out of ~60K doses, ONLY ~500 received COVAXIN. That's hardly 1%.
f
If Covaxin sells for their asking price (Rs. 1200/dose) in private centers, access to it might be easier for people who can afford it.
m
You know, there were stuff being said around that some people are getting doses for around 1.2 lacs in black. Which is really sad. But I am not def not surprised.
f
What an absolute clusterf*ck.
s
I would personally go for Covisheild. No peer reviewed 3rd phase data makes me suspicious of covaxin. Though I am not taking it until my parents complete both doses & 14 days after that
Also I believe 30+ should get it right now since they are out working compared to us in our early 20’s
f
s
ty Kushal 😄 looks like even better for us since we got the choice now and no monopoly 🙌
f
Are you sure we have a choice? From what I read you only get to choose the appointment and you cannot pick the vaccine
s
by choice I meant we can inquire which center has which one and go there if we have a specific preference.
Mumbai had covisheild up until now though, so rare chances. But Rajasthan had both iirc
f
I believe if we’re paying for it, we can choose not to take if the place is giving the vaccine which we don’t want.
👆 1
c
Just to be clear the rational choice is to avoid COVAXIN. The phase 3 data is still not available. And imagine the vested interested in phase 3 data coming out after ~20 million people would have been administered the vaccine! Even if the vaccine does what is claimed, it will be virtually unverifiable and beyond public discourse to correct. Even the interim papers (one was published by a direct relation of the company, funded by the company, with no disclosures, claiming that the vaccine is effective against mutated strains, even before the general efficacy was clear from broader trials!). Also to clarify something critical, a vaccine that creates symptoms mimicking the disease immediately after is a sign of effectiveness; and should be stronger for a rotavirus compared to the other vaccines. If you are going to go by anecdotal logic, please flip the results. My sincere request is to always go to the original papers/data, and look at what is being said. It is far more accessible than you think. Don’t fall for the Chinese whispers that reaches you through pop-culture. 2 important DISCLAIMERS: 1. I am not a medical professional, so none of this is to be misconstrued as advice. 2. I am (distantly) related to Bharat Ella, and although I cannot say more, I know enough to say that I will not trust the data
The way things are right now, I am going to also say this: if anybody thinks this (☝🏾) is misinformation, please just tell me and don’t report me to the police! 😔
c
@flat-morning-91037 Interesting. I heard the quite opposite reviews, where covishield is performing far better and less side effects than covaxin.
d
At this point my main worry is covaxin needs to ramp up production and actually deliver (they have talked of 700m doses a year, but when that ramp up starts is still unknown) Covishield will ramp up to 100m from current 65m doses a month by june
@flat-morning-91037 just because Google is, well, Google, do you trust every product they make?
The criticism of covaxin was deserved. Especially in the context of us asking approved vaccines with phase 3 results like Pfizer to make bridging studies while allowing a vaccine with no phase 3 data
Brazil has also rejected them saying the process they have doesn't assure that the virus is fully inactivated
It was pure vaccine nationalism
f
@damp-coat-97256 Not being political here, but I didn’t follow just random news articles to determine what vaccine is good or not. Preferring Covaxin over Covishield doesn’t make Covishield automatically bad (I have family members who took first doses of both). Lancet did publish reviews of Covaxin both in January (
<https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30942-7/fulltext>
) as well as in March (
<https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00070-0/fulltext>
), and it warranted efficacy of it against multiple strains. Besides, Pfizer’s vaccine didn’t get approval in India not only due to lack of bridging trials but their demand of full indemnity against potential lawsuits (
<https://theprint.in/health/why-indias-expert-panel-rejected-emergency-use-nod-for-pfizer-vaccine/599529/>
), to which govt. denied. Sputnik got approval because they agreed to both; bridging trials as well as no indemnity. 🙂 Having said that, I personally would get Covishield in case preferring Covaxin means a wait for multiple weeks. The preference for me is applicable only when both are readily available.
👍 3
d
But after Sputnik was approved now all well known regulator vaccines are approved including pfizer right. And bridging equivalent is being done with first 100 recepients etc. Could have been the call then. I actually admire Krishna Ella. Bharat Biotech is great, but we took a step that lowered confidence of people and we're inconsistent with that. Its politics, because it was a political decision and not a scientific one, would you disagree?
As of now covaxin looks like the best, but that's hindsight Could have been like sinovac and even Krishna Ella would agree to that.
Btw January one was phase 1 and March was interim results right. While every other approved vaccine across world were done after phase 3 results
My main point - it wasn't disinformation and past success doesn't mean something will work too
f
- With the case load that India had. - The logistical limitations of western vaccines (temperature requirements both for storage and transport). - Supply scarcity due to most countries hoarding the stock more than needed as well as higher price per dose. - Several vaccine makers not agreeing to the terms set by DGCI India. Did we have any other option except to rely on two available vaccines we had in January? Not to mention that SII already had export commitments to EU countries so not everything they manufactured belonged to us.
d
Yes but when it was approved I was thinking Covaxin had the production bandwidth to match or overtake SII commitments to India but as we see it's 90% covishield. We could have waited for the interim result in March and taken a step and no real effect on vaccination campaign
If they were so confident they could have stockpiled like SII did and then immediately sent them across in mid march
f
I guess we’d never know what stopped BB from manufacturing early on, may be SII is largest manufacturer for a reason. Besides, even with jabs available by both manufactures, we’ve run out of stocks in multiple places, having only 1 supplier would’ve only made it worse (including an absolute monopoly).
d
Now, but I am saying wait till mid March if phase 3 interim results are coming
At that time we had enough supply and demand was low
They would have done Max about 6m doses at that time I believe and not a big difference but the boost of a fully tested indian vaccine would have been immense
While many did use this as opportunity to oppose and spread disinformation, the genuine concerns were still valid. Could have avoided all that. A misstep for sure
c
Where is this “Covaxin is better than Covishield” coming from? Can anybody please point me to any peer reviewed data?
Wait, which incompetent newspaper is this? 80L people were registered - not booked vaccine slots! Even the (abominable) publicity for the vanity metrics does not claim this: https://twitter.com/drharshvardhan/status/1387447694105276424?s=20