Hi! I am working with single-cell RNAseq generated from 10x Chromium Multiplex. There are two runs/pools (A and B) with D1-1,2,3 and D2-1 in Pool A and D2-2 and D3-1,2 and D4-1 in Pool B. I am not sure, when the normalization of the counts after filtered should be done. Should it be done after combining or before combining the pools?