Bioinformatics is a field of research, machine learning (and AI) is a technology, which can be applied to many different fields, so these two are somewhat orthogonal, so it's not an either/or, but an and (assuming you want to combine both).
I don't see anything wrong with your résumé, but you probably noticed that the big buzz word of 2026 is "AI", so if you can find an excuse to mention that somewhere, it could be helpful (especially if your résumé is scanned by some algorithm).
What I would suggest is that you look at job ads (academia or industry, or both, depending on what you feel like doing), pick the ones where you say, "Hey, this is cool, I want to do that!", and then make sure your résumé looks interesting to the people who posted those ads. Looking through all these job descriptions will also give you a very good idea of what topics are "hot" at the moment. Good luck!