Does anyone here have experience with using

snpsift annotate

vs

snpsift annotatemem

? https://pcingola.github.io/SnpEff/snpsift/annotate/ and https://pcingola.github.io/SnpEff/snpsift/annotate_mem/ I am thinking about adding it to the pipeline.

annotatemem

looks a lot more convenient for allowing multiple databases without implementing some crazy channel logic, but I haven't seen much about this subcommand around. I am mostly wondering about stability in comparison to snpsift annotate