I have a question about the anndata → Seurat conversion.
Currently, the conversion fails if the resulting sparse matrix exceeds ~2^31 non‑zero entries (R’s Matrix package limit). This usually only surfaces when combining the datasets at the end.
I know that very large datasets can be handled via BPCells‑backed Seurat objects, but these require absolute paths and are harder to share in a core‑facility setting.
Is there a better way to store this size as an Seurat object?
(Currently, the process is just turned off, but would be nice to have the conversion included in the future)