One more question - if I wanted to add another HTO multiplexing tool to the hadge toolbox for example "demuxmix" , would you be open to that ?| (https://academic.oup.com/bioinformatics/article/39/8/btad481/7234612)

Thanks! I'm a bit worried about it already being completely dead. The last commit was basically when it got published (2 years ago). What do you think?

oh I see, I hadn't looked much at the github repo as its on bioconductor but we have been using it in the lab quite a bit and found it working pretty well

Yeah that might be true but I guess it's just a matter of time till it breaks - sadly

@Leon B, thank you for your questions! We discussed adding

demuxmix

to hadge in our last meeting. As Lukas mentioned, we are not sure whether this package will be maintained in the future. That was also the reason why we dropped

scSplit

. So we currently see no reason to implement it. But we can also do it this way: If you still believe that this package should be added to the pipeline, please create a GitHub issue. If there is enough feedback from the community, we can then add it to hadge.

Ok, maybe its not worth the hassle