any interest in passing -O *.sto to hmmbuild so we...
# proteinfamilies
m
any interest in passing -O *.sto to hmmbuild so we can use the cons seq later for a curation by --hand?
šŸ‘Œ 1
e
I'd say yes! If you could update the
HMMER_HMMSEARCH
to do that (similarly to the other passed flags with files (-A, --tblout and --domtblout)), and then we can update in #C07URFZF074 and output that by default. Feel free to tag me as reviewer
m
HMMER_HMMBUILD
? šŸ˜„
e
Oh, the -O flag can go into both šŸ˜„ Ofc, in #C07URFZF074 we will have to decide at which point to do that automatically (if additional sequence recruitment is enabled, then we do this at the
hmmsearch
step, otherwise at
hmmbuild
. So I guess we'll have to update both modules in one go šŸ˜‰
m
Ah thanks, but I did a test and re-read the manual which states: "-O writes an ā€œannotated, possibly modifiedā€ source alignment, and that some residues may be shifted to satisfy Plan7 constraints, specifically because Plan7 does not allow insert→delete transitions" so for my use-case the coords don't match the seed alignment. I'm gonna leave it as is šŸ˜„