Hi <!here>, oncoanalyser 2.3.0 has been released, notable changes include:
Tooling
_BamTools_: run only on specified regions in targeted mode
_CIDER_: performance improvements
_SAGE_: run MT calling by default, improve germline filters
_PURPLE_:
⢠new outputs CNV (chromosome arm data; region-specific data)
⢠new amplification / deletion thresholds in driver gene panel file
_LINX_: new CN data tracks for targeted sequence data
Other
Removed custom re-mapping for ALT alignments prior to LILAC
Enabled GH Actions nf-test workflow for pipeline tests (using minified simulated t/n WGTS data)
Added HCC1395 tumor / normal WGS (depths respectively 80x, 40x) and tumor WTS for full test profile
Improved samplesheet validation
See here for the oncoanalyser
CHANGELOG.md and
Release notes. Thanks to everyone involved in this release and to the Hartwig folks for tooling updates and contributing recommended changes