perf should be relatively good on large web pages, and web sites with lots of pages don't really factor in how well it performs. There is one current issue I am aware of with history support in mobile safari when pages are slow, but otherwise it should be pretty clean across the board. We test in Chrome, Firefox and Safari before most releases:
https://htmx.org/test/. (Where "we" is me, on my phone and laptop. 🙂