i want cdn.*\*\*\*.lol/* to show \*\*\*\*.lol/uploads*

You'd have to use a Worker to transform the paths, and you'd be paying for each request as a worker invocation, no easy way If you could have cdn subdomain point to the same origin/host and have it accept the cdn subdomain as well, you could then just use a transform rule to rewrite the path and append /uploads to it

Don't origin rules also allow you to achieve something like that?

with ent you could go with the second idea there with a transform rule and use an origin rule/page rule to rewrite the host header/change dns lookup if you couldn't also allow cdn