i would try with numeric backreferences, i honestl...
# fw1
w
i would try with numeric backreferences, i honestly haven't done routes like you have above. something like
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{ "/(north|east|midlands|london|southeast|southwest|moreregions)+/?$" = "/home/region/region/\1" },
		{ "/(north|east|midlands|london|southeast|southwest|moreregions)+/([A-Za-z0-9-_])+/?$" = "/home/area/region/\1/area/\2" }