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would it be feasible to prepare an off platform tuple sketch( basically non time data) and supply it as a set intersection with a tuple sketch in a druid data source?

This will be useful https://blog.hellmar-becker.de/2022/12/26/ingesting-data-sketches-into-apache-druid/

a set intersection with a tuple sketch in a druid data source?

THETA_SKETCH_INTERSECT

may be useful here ( https://druid.apache.org/docs/latest/tutorials/tutorial-sketches-theta.html)