I think the easiest way to do this is creating new workpsaces on each machine, and adding only the vaults you want. The downside is that the config is not backed up or synchronized. Using self contained vaults could help, for example if you want all your vaults available at home and only the work vault available at work, you could just open your work vault and use that. But self contained vaults is still early preview, so not all features work yet and bugs are expected.